Injection treatment for younger, brighter skin Part of the body: face, including forehead, brow bone, periorbital area and cheekbones.| Neck, décolleté and hands.| Objective: Treatment administered alone and for preventive or anti-aging purposes: improves the quality and brightness of the skin, strengthens the structure and general elasticity of the skin. 1| The SET (Skin Enhancement Technique) technique improves the quality of the skin and prepares it to receive other aesthetic medicine interventions: laser, radiofrequency, hyaluronic acid injections, peeling, microneedling and surgery. 2| Clinically proven safety and effectiveness Long Chain Polynucleotides in improving skin structure and elasticity for a more youthful appearance. 2 A clinical study on skin biorevitalization using long-chain polynucleotides was conducted on 143 patients, aged between 32 and 75 years, before and 30 days afterultima treatment session, according to two protocols for the face, neck, décolleté and back of the hands :| A prevention treatment, for young skin, consisting of 3 intradermal treatment sessions (one every 3 weeks), followed by a possible maintenance session every 2-3 months.| A more intense treatment for more mature skin, consisting of 4 sessions (one every 1-2 weeks), followed by any maintenance sessions every 3 months.| Effectiveness: 91% of patients showed a clinically proven physician-assessed decrease in superficial wrinkles* +14.7% improvement in skin hydration compared to baseline** +21.8% improvement in skin elasticity **| Safety: The product was very well tolerated and the injections did not cause excessive pain. No serious adverse effects have been reported due to the high biocompatibility of the gel/product.| In over 90% of subjects, PN-HPT® technology allowed for a general improvement in skin texture and a reduction in superficial wrinkles 5,6 | 1 PhilArt Notice 2 Cavallini M, Papagni M. Long Chain Polynucleotide Gel and Skin Biorevitalization. International Journal of Plastic Dermatology-ISPLAD. 2007; 3(3): 27-32. 3 Cavallini M, Bartoletti E, Maioli L, Massirone A, Pia Palmieri I, Papagni M et al. Consensus report on the use of PN-HPT™ (highly purified polynucleotide technology) in aesthetic medicine. J Cosmet Dermatol. 2021 March;20(3):922-928. doi:10.1111/jocd.13679. Epub 2020 Sep 21. PMID: 32799391; ID PMC: PMC7984045. 4 Araco A, Araco F. Preliminary, prospective, randomized study of highly purified polynucleotide versus placebo in the treatment of moderate to severe acne scars. Aesthet Surg J. 2021 June 14;41(7):NP866-NP874. doi:10.1093/asj/sjab125. PMID: 33755110. 5 Massirone A. Polynucleotides Highly Purified Technology and facial skin, a story of innovative skin priming. Aesthetic medicine.2021 January-March;Vol.7(1):25-40. *The doctor's overall assessment at the follow-up visit was positive. In 91% of patients the doctor observed a clinical improvement (improvement in 73% and clear improvement in 18%) with a reduction in superficial wrinkles and a better, more toned appearance of the skin. More specifically, this result was observed on the face, in particular on the cheekbones, periorbital area and neck. **Patient evaluation using a digital skin measurement system (Callegari Soft 5.5). The assessments were recorded before and one month after the end of treatment. | These medical devices are for strictly medical use, their use is strictly reserved for qualified doctors specially trained in aesthetic techniques. | | For any questions, please contact our pharmacist via email at the following address: pharmacist@parapharmadirect.com
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