Abiogen pharma spa Jonexa Up 2% Intra-Articular Syringe 4.4ml

Jonexa UP 2% Intra-Articular Syringe - Medical Device Biocompatible hydrogel of cross-linked sodium hyaluronate obtained by biofermentation and highly purified, dissolved in a physiological and isotonic buffer. The product is an injectable, sterile and apyrogenic hydrogel, with a low level of endotoxins. JONEXA UP is formulated with highly purified sodium hyaluronate, quality salts compliant with the requirements reported in the Pharmacopoeia and water for injections. JONEXA UP reduces pain and increases the functionality of the affected joint. JONEXA UP provides a lubricating and shock-absorbing effect on the affected joint. JONEXA UP improves the patient's quality of life. JONEXA UP must essere administered by intra-articular injection by a qualified physician following all rules regarding aseptic procedure and injection technique. | JONEXA UP must essere injected with a suitable sterile needle (18-21G needles are recommended). | It is recommended that JONEXA UP be administered in a single session. The amount of product to be administered is at the discretion of the specialist. Discard any unused portion of the syringe. | Directions for use JONEXA UP must essere injected into the joint in the synovial space of the knee, as a means of viscosupplementation for the synovial fluid, when the viscosity of the fluid is reduced due to the osteoarthritis process, in patients who have not responded adequately to conservative non-pharmacological therapy and simple analgesics. 1. Before the injection, the area to be treated must essere disinfected thoroughly and the product must essere brought to room temperature.| 2. Open the sterile packaging and remove the syringe from inside.| 3. Remove the syringe tip cap without touching it, to keep it sterile.| 4. Connect a suitable sterile needle (18-21G needles are recommended) to the tip of the syringe.| Ensure that the needle is properly locked onto the syringe's Luer-lock adapter before using it.| 5. Remove air from the syringe, if necessary.| 6. Inject into the joint in the synovial space of the affected knee, following aseptic injection procedures.| 7. At the end of the treatment session, discard the syringe and any remaining product.| The amount of product to be administered is at the discretion of the medical specialist; the recommended dose is 3-4 ml for each knee joint.| Components Cross-linked sodium hyaluronate 20 mg/ml, disodium phosphate dodecahydrate 0.6 mg/ml, sodium dihydrogen phosphate dihydrate 0.05 mg/ml, sodium chloride 8 mg/ml, water for injections qs | Warnings Do not administer JONEXA UP to patients with known hypersensitivity (allergy) to hyaluronic acid and/or other components of the product. | Do not administer JONEXA UP to patients with acute or chronic dermatological disorders or with inflammatory and/or infectious skin problems. | Do not administer JONEXA UP to patients with coagulation disorders and/or being treated with anticoagulant drugs. | JONEXA UP must not be administered to patients with coagulation disorders and/or being treated with anticoagulant drugs. essere administered to pregnant or breastfeeding women.| JONEXA UP should not essere administered to children.| The use of JONEXA UP in any joint other than the knee and for other conditions has not been studied.| JONEXA UP must essere JONEXA UP must be strictly injected into the intra-articular space following aseptic injection procedures. essere administered with sterile Luer-lock needles. | Do not inject into a blood vessel or surrounding tissue. To avoid pain after the injection, it is recommended to keep the local injection site still. The product should not essere used if the packaging is damaged or broken. | The product must not essere used after the expiration date. | The product is for single use only. Do not reuse; risk of infection. | Do not resterilize; resterilization may affect the physicochemical properties of the product and compromise its efficacy and safety. | The used syringe and needle must essere Discard in an appropriate container. Keep out of reach of children. Do not use with other products containing quaternary ammonium salts such as benzalkonium chloride or with any surgical material treated with these types of substances, as sodium hyaluronate may precipitate in their presence. To prevent any possible interaction, avoid co-administration with other intra-articular products. No interactions with other local anesthetics are known. Storage: Store between 5°C and 25°C. Protect from light and avoid freezing. Do not use after the expiry date indicated on the package. Format: 4.4 ml syringe.